Publications
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2016
HMGB1 Protein: A Therapeutic Target Inside and Outside the Cell
I Ugrinova, E Pasheva
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2016
The repair capacity of lung cancer cell lines A549 and H1299 depends on HMGB1 expression level and the p53 status
S Yusein-Myashkova, I Stoykov, A Gospodinov, I Ugrinova, E Pasheva
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2016
Non-histone protein HMGB1 inhibits the repair of damaged DNA by cisplatin in NIH-3T3 murine fibroblasts
S Yusein-Myashkova, I Ugrinova, E Pasheva
PMID: 24325815
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2015
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
Patel A, Lee HO, Jawerth L, Maharana S, Jahnel M, Hein MY, Stoynov S, Mahamid J, Saha S, Franzmann TM, Pozniakovski A, Poser I, Maghelli N, Royer LA, Weigert M, Myers EW, Grill S, Drechsel D, Hyman AA, Alberti S.
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2015
Centrosomal nucleolin is required for microtubule network organization
X Gaume, AM Tassin, I Ugrinova, F Mongelard, K Monier, P Bouvet
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2015
Interdependence of expression level of high mobility group box protein 1 and tumour suppressor protein p53
S Yusein-Myashkova, I Ugrinova, E Pasheva
Comptes rendus de l‘Ácademie bulgare des Sciences 68 (12), 1541-1546 2015
PMID: 25590348
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2015
The synthesis of recombinant HMGB1 protein in E.coli is modulated by its C-terminus domain
Todorova, J., E. Pasheva
Comptes rendus de l‘Ácademie bulgare des Sciences, 68
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2015
Combined treatment of cancer cells with the new anti-neoplastic agents erufosine and doxorubicin
V Uzunova, A Georgieva, S Apostolova, I Ugrinova, R Toshkova
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2014
The subunits of the S-phase checkpoint complex Mrc1/Tof1/Csm3: dynamics and interdependence
Uzunova SD, Zarkov AS, Ivanova AM, Stoynov SS, Nedelcheva-Veleva MN
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2014
Antimycobacterial activity generated by the amide coupling of (−)-fenchone derived aminoalcohol with cinnamic acids and analogues
I Slavchev, GM Dobrikov, V Valcheva, I Ugrinova, E Pasheva, V Dimitrov
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2014
Novel glass slide preparation system for single DNA molecules analysis
Zarkov A, Stoynov S, Nedelcheva-Veleva M.
Biotechnol Biotechnol Equip. 2014 Jan 2;28(1):112-117
PMID: 26019496
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2014
Enantiopure antituberculosis candidates synthesized from (−)-fenchone
GM Dobrikov, V Valcheva, Y Nikolova, I Ugrinova, E Pasheva, V Dimitrov
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2013
Efficient synthesis of new (R)-2-amino-1-butanol derived ureas, thioureas and acylthioureas and in vitro evaluation of their antimycobacterial activity
Georgi M. Dobrikov , Violeta Valcheva, Yana Nikolova, Iva Ugrinova, Evdokia Pasheva, Vladimir Dimitrov
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2013
Novel fluorescent dyes for single DNA molecule techniques
Zarkov A, Vasilev A, Deligeorgiev T, Stoynov S, Nedelcheva-Veleva M.
Molecular Imaging Journal, 1;12(2):90-9
PMID: 23415397
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2013
The thermodynamic patterns of eukaryotic genes suggest a mechanism for intron-exon recognition
Nedelcheva-Veleva MN, Sarov M, Yanakiev I, Mihailovska E, Ivanov MP, Panova GC, Stoynov SS.
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2013
The chaperone like function of the nonhistone protein HMGB1
Osmanov T, Ugrinova I, Pasheva E.
Biochemical and Biophysical Research Communications, 8;432(2):231-5
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2012
High mobility group B1 protein interacts with its receptor RAGE in tumor cells but not in normal tissues
Todorova J, Pasheva E.
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2012
Interaction of nucleolin with ribosomal RNA genes and its role in RNA polymerase I transcription
Cong R, Das S, Ugrinova I, Kumar S, Mongelard F, Wong J, Bouvet P.
Nucleic Acids Research, 40(19):9441-54. 1
PMID: 22859736
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2012
The effect of PKC phosphorylation on the "architectural" properties of HMGB1 protein
Ugrinova I, Zlateva S, Pasheva E.
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2011
Cyclin-dependent kinase 5 phosphorylates mammalian HMGB1 protein only if acetylated
Ugrinova I, Pashev IG, Pasheva EA.
The Journal of Biochemistry, May; 149(5):563-8
PMID: 21257610
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2011
The DNA binding and bending activities of truncated tail-less HMGB1 protein are differentially affected by Lys-2 and Lys-81 residues and their acetylation
Elenkov I, Pelovsky P, Ugrinova I, Takahashi M, Pasheva E.
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2010
In vitro pharmacological study of monomeric platinum(III) hematoporphyrin IX complexes
Momekov G, Karaivanova M, Ugrinova I, Pasheva E, Gencheva G, Tsekova D, Arpadjan S, Bontchev PR.
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2010
The expression of HMGB1 protein and its receptor RAGE in human malignant tumors
Kostova N, Zlateva S, Ugrinova I, Pasheva E.
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2009
In vitro biochemical and pharmacological evaluation of a novel cytotoxic dinuclear platinum(II) complex with 3-amino-5-methyl-5-phenylhydantoin
Momekov GTs, Ugrinova I, Pasheva EA, Bakalova AG, Varbanov HP, Ferdinandov DV, Ivanov DS, Konstantinov SM.
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2009
Nucleosome binding properties and Co-remodeling activities of native and in vivo acetylated HMGB-1 and HMGB-2 proteins
Ugrinova I, Pashev IG, Pasheva EA.
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2009
Native HMGB1 protein inhibits repair of cisplatin-damaged nucleosomes in vitro
Ugrinova I, Zlateva S, Pashev IG, Pasheva EA.
The International Journal of Biochemistry & Cell Biology, 41:1556-62
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2009
Interplay between in vitro acetylation and phosphorylation of tailless HMGB1 protein
Pelovsky P, Pashev IG, Pasheva E.
Biochemical and Biophysical Research Communications, 380:138-42
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2009
Post-synthetic acetylation of HMGB1 protein modulates its interactions with supercoiled DNA
Ugrinova I, Pashev IG, Pasheva EA.
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2009
Immunochistochemical determination of HMGB1 protein level in human malignant tumours
Kostova N, Zlateva S, Pasheva E.
Comptes rendus de l"Academie Bulgare des Sciences, 62:229-232
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2008
HMGB1 protein inhibits DNA replication in vitro: a role of the acetylation and the acidic tail
Topalova D, Ugrinova I, Pashev IG, Pasheva EA.
The International Journal of Biochemistry & Cell Biology, 40:1536-42
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2008
Mutagenesis at the sites of postsynthetic acetylation of the non-histone protein HMGB-1 and its truncated form
Pelovsky P, Pasheva E.
Comptes rendus de l"Academie Bulgare des Sciences, 61:1151-1158
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2007
DNA bending versus DNA end joining activity of HMGB1 protein is modulated in vitro by acetylation
Ugrinova I, Mitkova E, Moskalenko C, Pashev I, Pasheva E.
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2007
Stability of mRNA/DNA and DNA/DNA duplexes affects mRNA transcription
Kraeva RI, Krastev DB, Roguev A, Ivanova A, Nedelcheva-Veleva MN, Stoynov SS.
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2006
Coordination of DNA synthesis and replicative unwinding by the S-phase checkpoint pathways
Nedelcheva-Veleva MN, Krastev DB, Stoynov SS.
Nucleic Acids Res. 2006;34(15):4138-46
PMID: 16935878
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2005
The inhibitory effect of HMGB-1 protein on the repair of cisplatin-damaged DNA is accomplished through the acidic domain
Mitkova E, Ugrinova I, Pashev IG, Pasheva EA.
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2004
In vitro acetylation of HMGB-1 and -2 proteins by CBP: the role of the acidic tail
Pasheva E, Sarov M, Bidjekov K, Ugrinova I, Sarg B, Lindner H, Pashev IG
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2001
In vivo acetylation of HMG1 protein enhances its binding affinity to distorted DNA structures
Ugrinova I, Pasheva EA, Armengaud J, Pashev IG.
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1998
Preferential binding of high mobility group 1 protein to UV-damaged DNA. Role of the COOH-terminal domain
Pasheva EA, Pashev IG, Favre A.