Current projects

A list of the most significant scientific publications for which the services of the Center for Advanced Light Microscopy have been used:

1. Andreev V, Hristova R, Asparuhova M, Danovski G, Stoynov S, Gospodinov A. Mammalian INO80 chromatin remodeler cooperates with FANCM to mediate DNA interstrand crosslink-induced checkpoint activation and repair., DNA Repair 2019 Feb;74:38-50. IF 4.5

2. Krastev, DB, Pettitt, SJ, Campbell, J, Song, F, Tanos, BE, Stoynov SS, Ashworth, A, Lord, CJ. 2018. Coupling bimolecular PARylation biosensors with genetic screens to identify PARylation targets. Nature Communications , 9 (1), pp 2016. IF 12

3. Pettitt S.J., Krastev D.B., Brandsma I., Drean A., Song F., Aleksandrov R., Harrell M., Menon M., Brough R., Campbell J., Frankum J., Ranes M., Pemberton H. N., Rafiq R., Fenwick K., Swain A., Guettler S., Lee J., Swisher E. M., Stoynov S., Yusa K., Ashworth A., Lord C. J., 2018. Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance. Nature communications , 9 (1), pp 1849. IF 12

4. Aleksandrov R., Dotchev A., Poser I., Krastev D., Georgiev G., Panova G., Babukov Y, Danovski G., Dyankova T., Hubatsch L., Ivanova A., Atemin A., Nedelcheva-Veleva M. N., Hasse S., Sarov M., Buchholz F., Hyman A, Grill S. W., Stoynov S., 2018. Protein Dynamics in complex DNA lesions. Molecular cell , 69 (6), pp.1046-1061. IF 14.7

5. Patel, A., Lee, H.O., Jawerth, L., Maharana, S., Jahnel, M., Hein, M.Y., Stoynov, S., Mahamid, J., Saha, S., Franzmann, T.M. and Pozniakovski, A., A, Poser I, Maghelli N, Royer L, Weigert M, Myers E, Grill S, Drechsel D, Hyman A, Alberti S. 2015. A liquid-to-solid phase transition of the ALS protein FUS accelerated by disease mutation. Cell , 162(5), pp.1066-1077. IF 32

6. Vassileva I, Yanakieva I, Peycheva M, Gospodinov A and B. Anachkova, The mammalian Ino80 chromatin remodeler is required for replication stress recovery., Nucleic Acids Res. , 2014, 42 (14), p. 9074-86 IF 9

7. Uzunova, S.D., Zarkov, A.S., Ivanova, A.M., Stoynov, S.S., Nedelcheva-Veleva, M.N., The subunits of the S-phase checkpoint complex Mrc1/Tof1/Csm3: Dynamics and interdependence, Cell Division 9(1),4, 2014

8. Zarkov A., Stoynov S. and Nedelcheva-Veleva MN., Novel glass slide preparation system for single DNA molecules analysis, Biotechnology and Biotechnological Equipment , 28, (2014), 112-117